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What is Carpal Tunnel Syndrome?
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Generic drug clopidogrel for the primary prevention of CV death in secondary prevention populations: a randomized trial." Ann Intern Med. 157 Lopid 300mg $374.98 - $1.39 Per pill (6): 577-87. Matsumoto C, Kawarase M, Ishita et al. "Clopidogrel reduced myocardial infarction hospitalizations and mortality among patients with a first MI." J Am Coll Cardiol. 2007 Jan;51(1):35-43. Miller M. "Clopidogrel clopidogrel generic cost reduces hospital-acquired infections." J Clin Pharm Ther. 2005 Jul;28(3):297-303. Moran M. "Clopidogrel for secondary prevention of CV death: a prospective clinical trial." Am J Med Sci. 2001 May 20;317(11):1417-21. Moser J, Eiseman Hahn R. "Clopidogrel for secondary prevention of CV mortality: a randomized controlled trial." Mayo Clin Proc. 2002 Mar 1;80(2):249-55. O'Donohue R, Sjogren J, Kvamme S, et al. "Clopidogrel: a novel angiotensin-converting enzyme inhibitor with good antithrombotic properties: a double-blind placebo-controlled trial." Eur J Clin Pharmacol. 2007 Aug 11;63(8-9):611-9. Shen R, Yang F, Wang et al. "Comparison of thrombolytic and anticoagulant drug regimens in the prevention of CV events and all-cause mortality in the secondary prevention of myocardial infarction: a randomized controlled trial." JAMA. 1997 Dec 15;276(17):2114-5. Siegel H, Shih W. "Clopidogrel-mediated treatment for primary myocardial infarction: a randomized trial." Ann Pharmacother. 2005 Jun;36(6):741-50. Siegel H, Shih W. Safety of the angiotensin-converting enzyme inhibitor, clopidogrel, as a primary preventive therapy for CV mortality." Am J Med Sci. 2009 Nov;362(11):1741-5. Shih W, Shigemoto V, Yamada K, et al. "Clopidogrel prolongs life without significantly reducing CV events compared with aspirin in high-risk Japanese patients with drug stores in canada online acute coronary syndromes." Ann Pharmacother. 2004 Mar;35(3):347-53. Sloterdijke E, van Staveren W. "Clopidogrel for secondary prevention of ischemic CV events in the secondary prevention of heart disease: an observational meta-analysis of randomized clinical trials." Eur J Cardiovasc Prev Rehabil. 2010 Sep;22(5):427.
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The carpal tunnel is a space in the wrist where the median nerve and 9 tendons pass. It is bound by bones on 3 sides and the transverse carpal ligament. Anything that increases swelling within the tunnel can increase pressure on the median nerve and inhibit blood flow and lead to injury. Since the median nerve innervates the thumb, index, middle, and half the ring finger, any injury can cause symptoms such as pain, numbness or tingling in these fingers. Severe damage can cause weakness in the thumb muscles over time. Common risk factors include age over 50, female gender, and pregnancy. Underlying medical problems can such as diabetes, hypothyroidism, rheumatoid arthritis, and fractures can make you susceptible. Exposure to vibration and repetitive motion can exacerbate the underlying condition, but not necessarily cause carpal tunnel. Repetitive stress syndrome is a separate entity from carpal tunnel and requires non-surgical treatment, mostly involving hand therapy and workplace modifications. | ||||||||||||